Tomislav Stankovski | ''Coupling functions in neuroscience''
Faculty of Medicine, Ss Cyril and Methodius University, Skopje 1000, Macedonia
Department of Physics, Lancaster University, Lancaster LA1 4YB, United Kingdom
Abstract: Interacting dynamical systems abound in nature and often the interest is not only to understand if, but also how they interact i.e. to reveal the functions and mechanisms that define and connect them. Coupling functions contain detailed information about the functional mechanisms underlying the interactions and prescribe the physical rule specifying how an interaction occurs [1]. Using a method based on dynamical Bayesian inference [2], we show how one can reconstruct and assess the coupling functions from phase dynamics of oscillatory data. Then, we present number of recent applications in neuroscience – including the neural cross-frequency coupling functions in eyes open/eyes closed resting state [3], and the state of general anaesthesia with two anaesthetics (propofol and sevoflurane) [4]; as we also present bursting neuronal coupling functions from multielectrode array (MEA) recordings of interacting neurons from rats.
References:
[1] Stankovski et al., Rev. Mod. Phys., (2017)
[2] Stankovski et al., Phys. Rev. Lett. (2012)
[3] Stankovski et al., Front. Syst. Neurosci. (2017)
[4] Stankovski et al., Philos. Trans. Royal Soc. A (2016)
For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)